From 444b80f55f64465d961b361a2b75ebd2582bc68f Mon Sep 17 00:00:00 2001
From: ACID Design Lab <82499756+acid-design-lab@users.noreply.github.com>
Date: Fri, 7 Jun 2024 00:46:41 +0300
Subject: [PATCH] Update README.md

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 README.md | 14 ++++++++++++++
 1 file changed, 14 insertions(+)

diff --git a/README.md b/README.md
index ddbf822..74ebbc7 100644
--- a/README.md
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@@ -127,3 +127,17 @@
 
    ![3d structure](https://github.com/acid-design-lab/DataCon24/assets/82499756/93b60dd2-b627-4c46-82c9-6127af4e26bb)
 
+### Modelling of interaction with membrane
+
+   For CPPs from 7 to 24 amino acids you can use PMIpred neural network model trained on Molecular Dynamics (MD) data to predict its interaction with the cellular membrane. Please use modelling on neutral membrane for better differentiation between CPPs and non-CPPs.
+
+   Example: 
+
+   CPP sequence FSLHRYMAWFCPWTGAWLMLD is predicted to **BIND** to the membrane.
+
+   ![image](https://github.com/acid-design-lab/DataCon24/assets/82499756/b43c427b-c504-471d-97f8-fee6988ffd22)
+
+   Non-CPP sequence is predicted **NOT TO BIND** to the membrane.
+
+   ![image](https://github.com/acid-design-lab/DataCon24/assets/82499756/2b559f32-b117-49a0-a3a2-a3298dabcd6c)
+