diff --git a/README.md b/README.md index 4c884d8..985e8e1 100644 --- a/README.md +++ b/README.md @@ -1 +1,50 @@ -# DataCon24 \ No newline at end of file +# DataCon 3.0 + +Data description: + +1. Mixed CPPs. +Contains CPPs with natural or modified amino acids. + + 1.1. POSEIDON + Contains heterogeneous experimental data regarding CPP (natural and non-natural amino acids) activity measurements (.csv format), which are: + 1) peptide name, + 2) target cell line CPP was tested on cell penetration ability, + 3) delivered molecule/protein, + 4) paper PubMed ID, + 5) cellular uptake measurement + measurement units, + 6) CPP+cargo concentration, + 7) incubation time, + 8) incubation temperature, + 9) determination method, + 10) uptake type, + 11) sequence + +2. Natural CPPs. +Contains only sequences with natural amino acids. + + 2.1. CPPBase + Contains sequences of CPPs with experimentally proved activity in .fasta format. + + 2.2. Experimental and Experimental2 + Contain more sequences of CPPs with experimentally proved activity in .txt format. + + 2.3. Experimental_high_uptake + Contain CPP sequences with high (but not stated) uptake in .txt format. + +3. Non-CPPs. +Contains negative CPP samples in .txt format. + + 3.1. Generated + Contains randomly generated sequences treated as negative. + + 3.2. Experimental + Contains non-CPP sequences shown not to demonstrate activity experimentally. + +4. Non-Natural CPPs. +Contains CPPs consisting of non-natural amino acids. + + 4.1. CPPBase_modified + Contains a list of modified CPPs with experimentally proved activity in .fasta format. + + 4.2. CPPBase_modified_symbols + Contains a list of abbreviations for modified amino acids in .txt format (ABBREVIATION: NAME; ...: ...).